In the 1920s Nenov studied in Germany. In 1931 he specialised in piano with Egon Petri. In the 1940s he became recognisable on the international piano performance scene. In 1949 he was on the jury of the Fourth Chopin Competition in Warsaw, which also included Margarita Long, and it was at this competition that Béla Davidovich won first prize.

Among his solo piano opuses, Sonata, Preludes, Cinema Suite, Toccata, Theme with Variations, Two Etudes, Dance, Miniatures, and his opuses for piano and orchestra, Fantasia and Ballade Concertante, his Piano Concerto (1932-1936) is notable. It is unusual in the scale of its four movements, contemporary and beautiful-sounding, powerful in energy, meaningful in its moments of contemplation, delicate in its national self-expression, masterly in terms of melody, involution, sense of structure, process and construction.